Open Access
Table 1.
The dynamics of hemostasis in piglets taken under observation
Registrated parameters | Catosal, n=21 | Control 1, n=21 | Control 2, n=32 | ||
---|---|---|---|---|---|
exodus | end of observation | exodus | end of observation | ||
The magnitude of the international normalized relationship | 1.14±0.14* | 1.22±0.12 | 1.12±0.07* | 1.13±0.16* | 1.22±0.09 |
The duration of the activated partial thromboplastin time, s | 30.4±0.79* | 37.2±0.63 | 30.8±1.03* | 26.3±0.84* | 37.1±0.69 |
The concentration of fibrinogen, g/l | 3.4±0.18* | 2.5±0.15 | 3.2±0.22* | 3.6±0.32** | 2.5±0.23 |
The concentration of soluble fibrin-monomer complexes, mg/dl | 3.3±0.19* | 2.4±0.17 | 3.1±0.26* | 3.9±0.19** | 2.6±0.82 |
Plasminogen activity level, % | 86.5±0.32* | 94.8±0.54 | 85.2±0.32* | 84.4±0.20* | 94.0±0.57 |
The activity of spontaneous platelet aggregation, units | 1.20±0.16* | 1.60±0.09 | 1.24±0.18* | 1.33±0.10** | 1.01±0.10 |
The activity of stimulated platelet aggregation with 0.5 pm ADP, units | 2.46±0.15* | 2.00±0.23 | 2.38±0.16* | 2.94±0.32** | 2.00±0.21 |
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