Download original image
A Classification of models adverse events during aging. Colour maps indicate “Norm” (green), “Risky” (blue tones), “RA” (orange), and “ImP” (rose) classes in the ageing populations. “Risky” class contains models showing ΔAPD90>6% events. Top frequency diagrams show results of age-related deviation of individual parameters, bottom diagram shows classification for 60 ageing populations with 4 parameter varied. Dashed line shows smoothed borderline between classes. B Fraction of ImP models and arrhythmogenic score dependencies on the age-related parameter deviation. Orange, green, red and purple lines show dependencies at GCaL, KNaCa, Gto and Vmax_up individual modulation, respectively. Black dots show scatter plots for 60 ageing models with blue linear regression lines (p < 0.01).
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.