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Table 2.
Percentages of each group that showed kidney and liver changes at day 90
| Group | Histological changes | % individuals | |
|---|---|---|---|
| Liver | Kidney | ||
| Control (K) | Hydropic degeneration | 0% | 0% |
| Fatty degeneration | 0% | 0% | |
| Necrotic | 0% | 0% | |
| Inflammation | 0% | 80% | |
| (+)‐2,2’‐Epicytoskyrin A dosage 6,25 mg/kg BW (P1) | Hydropic degeneration | 20% | 0% |
| Fatty degeneration | 0% | 0% | |
| Necrotic | 0% | 0% | |
| Inflammation | 0% | 60% | |
| (+)‐2,2’‐Epicytoskyrin A dosage 12,5 mg/kg BW (P2) | Hydropic degeneration | 0% | 0% |
| Fatty degeneration | 40% | 0% | |
| Necrotic | 0% | 0% | |
| Inflammation | 0% | 0% | |
| (+)‐2,2’‐Epicytoskyrin A dosages 25 mg/kg BW (P3) | Hydropic degeneration | 60% | 0% |
| Fatty degeneration | 0% | 0% | |
| Necrotic | 0% | 0% | |
| Inflammation | 0% | 80% | |
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