| Issue |
BIO Web Conf.
Volume 178, 2025
International Conference on the Future of Food Science & Technology: Innovations, Sustainability and Health (8th AMIFOST 2025)
|
|
|---|---|---|
| Article Number | 03015 | |
| Number of page(s) | 6 | |
| Section | Current Trends in Food Science & Technology | |
| DOI | https://doi.org/10.1051/bioconf/202517803015 | |
| Published online | 03 June 2025 | |
Effect of Turmeric (Curcumin) on Cancer Patients: A Comprehensive Review of its Anticancer Mechanisms, Clinical Efficacy, and Potential Therapeutic Applications
1
Research Scholar Department of Home Science, Faculty of Arts Social Sciences, Swami Vivekanand Subharti University, Meerut, 250002
2
Supervisor Department of Home Science, Faculty of Arts & Social Sciences, Swami Vivekanand Subharti University, Meerut, 250002
3
Assitant Professor, Department of home science, Faculty of arts and social science, Swami Vivekanand Subharti University, Meerut, 250002
* Corresponding author: Rupanshigarg1999@gmail.com
Turmeric, and its active constituent curcumin, have been the focus of much attention for their possible anticancer activity. This review will evaluate the effects of turmeric in cancer patients by examining its mechanism of action, clinical activity, and therapeutic efficacy. The main aim is to establish if curcumin is capable of preventing cancer growth and enhancing patient survival. The research strategy entailed an in-depth examination of available preclinical and clinical studies with a focus on the mechanisms of curcumin including antioxidant properties, anti-inflammatory activity, and induction of apoptosis in several cancer cell lines. The review also considered clinical trials evaluating the safety, bioavailability, and therapeutic efficacy of curcumin in cancer patients. Findings reveal that curcumin shows effective anticancer activities, including inhibition of tumor growth, metastasis, and induction of cancer cell apoptosis. Nonetheless, its clinical activity is compromised by its poor bioavailability, which has prompted the discovery of curcumin analogs and delivery systems to improve its therapeutic value. Certain clinical trials show favourable results, including diminished tumor markers and better quality of life among cancer patients. Finally, although curcumin has potential as an adjuvant therapy for cancer treatment, there is a need to enhance its bioavailability and develop standardized treatment modalities.
Key words: Curcumin / Anticancer properties / Tumor inhibition / Bioavailability
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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