| Issue |
BIO Web Conf.
Volume 182, 2025
The 3rd International Conference on Food Science and Bio-medicine (ICFSB 2025)
|
|
|---|---|---|
| Article Number | 01011 | |
| Number of page(s) | 4 | |
| Section | Food Science and Nutrition Research | |
| DOI | https://doi.org/10.1051/bioconf/202518201011 | |
| Published online | 02 July 2025 | |
Study on the extraction of flavonoids from Artemisia integrifolia and its anti-lung cancer activity
1 Department of Cardiothoracic Surgery, The First Hospital of Qiqihar, Qiqihar, Heilongjiang Province, 161006, China
2 College of Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang Province, 161006, China
3 Department of Chemotherapy, The First Hospital of Qiqihar, Qiqihar, Heilongjiang Province, 161006, China
Objective: To extract flavonoids from Artemisia integrifolia and determine their content, to evaluate their activity. Method: Total flavonoids were extracted using ultrasonic extraction, and the inhibitory effect on the proliferation of lung cancer cells H1299 was investigated. Additionally, a preliminary study was conducted on the treatment of liver degeneration. Results: Using a 50% ethanol solution, ultrasonic treatment at 90°C for 50 minutes followed by reflux for 3 hours resulted in the highest total flavonoid extraction rate. The study showed that it has a certain inhibitory effect on the proliferation of lung cancer H1299 cells, with an IC50 value of approximately 200μg/mL measured by MTT assay. The treatment also showed therapeutic effects on liver degeneration.
© The Authors, published by EDP Sciences, 2025
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