BIO Web of Conferences
Volume 2, 2014EPOV 2012: From Planets to Life – Colloquium of the CNRS Interdisciplinary Initiative “Planetary Environments and Origins of Life”
|Number of page(s)||10|
|Section||RNA World, Metabolisms Diversity and Complexification|
|Published online||18 February 2014|
Physico-chemical interactions between compartment-forming lipids and other prebiotically relevant biomolecules
1 Department of Biochemistry and Molecular Biology, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Basque Country, Spain
2 ANBioPhy, Molecular and Structural Archeobiology, UPMC Univ Paris 6, 75005, Paris, France
3 Dept. Biomolecular Engineering, University of California, Santa Cruz CA 95064, USA
Lipids are essential constituents of contemporary living cells, serving as structural molecules that are necessary to form membranous compartments. Amphiphilic lipid-like molecules may also have contributed to prebiotic chemical evolution by promoting the synthesis, aggregation and cooperative encapsulation of other biomolecules. The resulting compartments would allow systems of molecules to be maintained that represent microscopic experiments in a natural version of combinatorial chemistry. Here we address these possibilities and describe recent results related to interactions between amphiphiles and other biomolecules during early evolution toward the first living cells.
© Owned by the authors, published by EDP Sciences, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 2.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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