Passport and biological age in the choice of metabolic geroprophylactic therapy

¹ Ural State Medical University, 620028, Yekaterinburg, Sverdlovsk Region, Russian Federation
² Institute of Medical Cellular Technologies, 620026, Yekaterinburg, Sverdlovsk Region, Russian Federation

Abstract

We compared the effectiveness of geroprophylactic means of gas and metabolic therapy (hypoxytherapy, hyperbaric oxygenation, ozone therapy, dry carbonic baths, amino acid arginine, regulatory tripeptides H- Glu-Asp-Arg-OH u H-Lys-Glu-Asp-OH, interleukin-2 in medium therapeutic dosages by their ability to reduce biological age when tested on practically healthy people or patients with mild subclinical forms of polymorbid pathology at the age of 35 – 74 years. It has been established that the effectiveness of agents and effects in terms of the degree of decrease in biological age depends on the type of geroprophylactic agent, as well as in the part of research – the passport age of patients. In this case, the biological age of the subjects after treatment decreased in the range from 12.8 to 1.3 years, depending on the means used and, in some cases, on the passport age. The greatest efficiency was achieved after the use of a combination of peptide bioregulators in the age group with a passport age of 35 – 59 years. When prescribing metabolic geroprophylaxis, it is necessary to take into account, in addition to the indications and contraindications of the means used or the correction method, the state of the body, also the calendar age and the degree of decrease in biological age.