BIO Web Conf.
Volume 22, 2020International Conference “Longevity Interventions 2020” (ICLI 2020)
|Number of page(s)||8|
|Section||Problems of Gerontology and Geriatrics|
|Published online||06 July 2020|
Effect of age on the functioning of hemostasis system during hip joint endoprosthesis
Federal State Budgetary Educational Institution of Higher Education Ural State Medical University of the Ministry of Health of Russia, 620028, Repina st., 3, Yekaterinburg, Russian Federation
2 Institute of High-Temperature Electrochemistry of the Ural Branch of the Russian Academy of Sciences, 620990, Academicheskaya st., 20, Yekaterinburg, Russian Federation
3 State Autonomous Healthcare Institution of Sverdlovsk Oblast “Sverdlovsk Regional Clinical Hospital N°1” 620102, Volgogradskaya st., 18, Yekaterinburg, Russian Federation
* Corresponding author: email@example.com
The study was performed on 109 osteoarthritis patients who underwent hip joint endoprosthetics; the effect of age on changes in hemostasis system, blood loss level and deep veins thrombosis development in the background of standard prevention with low-molecular heparins were studied. Before the surgery, it was determined that 56 elderly patients (60.3 ± 6.4 years) compared to 53 middle-aged patients (41.8 ± 6.8 years) had a significantly higher initial and postoperative endothelial dysfunction, higher fibrin formation and lower anticoagulant potential; however, it was found that on the background of pharmacological anticoagulant therapy the changes in the hemostasis functioning in elderly patients did not lead to an increase of either blood loss or the number of thromboses.
Key words: hemostasis / hip joint endoprosthesis / elderly age / blood loss / thrombosis
© The Authors, published by EDP Sciences, 2020
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