Issue |
BIO Web Conf.
Volume 36, 2021
International Scientific and Practical Conference “Fundamental Scientific Research and Their Applied Aspects in Biotechnology and Agriculture” (FSRAABA 2021)
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Article Number | 06025 | |
Number of page(s) | 12 | |
Section | Topical Issues of Veterinary and Animal Science, Biotechnology of Production and Processing of Agricultural Products | |
DOI | https://doi.org/10.1051/bioconf/20213606025 | |
Published online | 01 October 2021 |
Mutational and phylogenetic status of west siberian strains of BLV
1 Novosibirsk State Agrarian University, 630039 Novosibirsk, Russia
2 State Research Center of Virology and Biotechnology “Vector”, 630559 Koltsovo, Novosibirsk Region, Russia
3 Research Institute of Experimental and Clinical Medicine, 630117 Novosibirsk, Russia
* Corresponding author: true_genetic@mail.ru
The study is devoted of full-genome BLV sequences circulating in cattle populations of the Novosibirsk region, Russia. The phylogenetic tree shows that the West Siberian isolates are quite closely related to such previously isolated strains as AF399704 (Brazil), AP018007, AP018016, AP018019, LC007988, LC007991 (Japan) and EF065638 (Belgium) we calculations show that the number of mutations that could independently occur in parallel evolving BLV strains significantly exceeds the expected number based on the probability of corresponding substitutions. It was also found that the studied isolates have some mutations, the presence of which, at first glance, is possible only with their divergent development in different independently evolving branches. However, calculations show that the probability of an independent origin of an identical mutation is extremely small, which indicates the possibility of exchanging RNA sites between isolates circulating in West Siberian cattle populations.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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