| Issue |
BIO Web Conf.
Volume 43, 2022
International Scientific and Practical Conference “VAVILOV READINGS-2021” (VVRD 2021) dedicated to the 101st anniversary of the discovery of the law of homological series and the 134th anniversary of the birth of N. I. Vavilov
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| Article Number | 03038 | |
| Number of page(s) | 6 | |
| Section | Biotechnologies | |
| DOI | https://doi.org/10.1051/bioconf/20224303038 | |
| Published online | 19 January 2022 | |
Study of Local Irritant Action of a Prototype Drug Based on Esters of Fatty Acids
Federal State-Owned Publicly-Funded Institution of Higher Education Saratov State Agrarian University named after N.I. Vavilov, Saratov, 1 Teatralnaya Ploshchad, 410012, Russian Federation
* Corresponding author: smirnova.ku@mail.ru
In this article, we have presented studies of the local irritating effect of a prototype wound-healing preparation based on water-based fatty acid esters with allantoin. The study of local irritant action included use of extreme dilutions of the drug for intradermal and local use in the induction and provocative phases. The assessment was carried out in points, in the experimental group it was on average 1 point, in control animals on average it was also equal to 1. These studies indicate that the composition has a mild skin reaction of sensitized guinea pigs and does not cause an allergic reaction.
© The Authors, published by EDP Sciences, 2022
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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