Persistence factors and antibiotic susceptibility of enterobacteria isolated from various animal species

Department of Epizootiology, Pathology, and Pharmacology, Samara State Agrarian University, town Ust-Kinelsky, 2, Uchebnaya St., Samara, 446442, Russian Federation

^* Corresponding author: Vladimir_21_2010@mail.ru

Abstract

During the study, we isolated 575 strains of enterobacteria from various animal species belonging to the genus Escherichia, Shigella, Salmonella, Klebsiella, Proteus, Providencia, Hafnia, Morganella, Enterobacter, Citrobacter, Serratia, Erwinia, Kluyvera, Yersinia. In farm animals, the amount of transient pathogenic enterobacteria Salmonella enteritidis and Yersinia enterocolitica did not exceed 0.22-0.12%. Among wild animals, the proportion of pathogenic Salmonella enteritidis and Yersinia enterocolitica did not exceed 0.24-0.11%, while Shigella dysenteriae and Shigella flexneri were isolated at a low concentration of 0.01%. In the feces of zoo animals, the amount of Salmonella enteritidis and Yersinia enterocolitica did not exceed 0.21-0.10%, while Shigella dysenteriae and Shigella flexneri were detected at the level of 0.01% of the total concentration of enterobacteria. The share of Salmonella enteritidis and Yersinia enterocolitica in domestic animals did not exceed 0.012-0.04%. Persistence factors in Salmonella enteritidis, Shigella dysenteriae and Shigella flexneri, Klebsiella oxytoca, and Yersinia enterocolitica were observed to be the highest among all isolated enterobacteria. Enterobacteria showed high resistance to benzylpenicillin from the group of natural penicillins to streptomycin, cephalothin from the group of cephalosporins of the first generation, polymyxin B, ofloxacin (tarivid), and metronidazole. Carbenicillin from the group of carboxypenicillins and piperacillin from the group of ureidopenicillins, kanamycin, amikacin, and gentamicin, cefepime from the group of IV generation cephalosporins, tetracycline, doxycycline and chloramphenicol, nalidixic acid, trimethoprim showed the highest antimicrobial activity against all cultures of enterobacteria isolated in this study.