| Issue |
BIO Web Conf.
Volume 59, 2023
2023 5th International Conference on Biotechnology and Biomedicine (ICBB 2023)
|
|
|---|---|---|
| Article Number | 02004 | |
| Number of page(s) | 6 | |
| Section | Precision Medicine and Drug Development and Preparation | |
| DOI | https://doi.org/10.1051/bioconf/20235902004 | |
| Published online | 08 May 2023 | |
Ethylene Oxide and Cancer: Digging for the Truth
College of Literature, Science, and The Arts University of Michigan, Ann Arbor, Ann Arbor, Michigan, USA
Multiple studies have shown a relationship between EO exposure and an increased risk of cancer in humans, but the results have been inconsistent. Nonetheless, the association between EO and human cancer risk, especially in terms of dose-response, is poorly understood. Examining whether or not EO exposure is linked to increased cancer risk in the basic adult population in the U.S. was the primary focus of this study. The study included data from both the 2013–14 and 2015–16 waves of the National Health and Nutrition Examination Survey (NHANES), for a total of 3,448 people. Data including demographic characteristics, medical history, and serum EO biomarkers were retrieved from Serum EO biomarker (hemoglobin adduct of EO (HbEO)) concentrations evaluated. Odds ratios (ORs) and 95% confidence intervals (CIs) were determined by multiple logistic regression. The result shows that EO with the highest concentration between 1340 and 1780(OR = 19.12, 95% CI: 1.73-211.47) is statistically significant.
© The Authors, published by EDP Sciences, 2023
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