BIO Web Conf.
Volume 59, 20232023 5th International Conference on Biotechnology and Biomedicine (ICBB 2023)
|Number of page(s)||4|
|Section||Clinical Trials and Medical Device Monitoring|
|Published online||08 May 2023|
Experimental study on aerosol inhalation of the human upper airway
School of Mechantronical Engineering, Changchun University of Science and Technology, Changchun, China
The study of aerosol deposition in the human upper respiratory tract is of great significance for understanding the impact of toxic aerosols on human health and improving the therapeutic effect of drug aerosol inhalation. 3D printing technology was used in the experimental model of the human upper airway. A laser particle size analyzer was used to study the deposition of aerosol particles with a particle size of 1-20 μm inhaled in the upper respiratory tract of the human body, and the particle deposition rules of the aerosol particles in the upper respiratory tract were analyzed. The experimental results show that aerosol particles remain more in the pharynx, larynx and position. For particles with a particle size of 1-5 μm, more deposition will occur in the trachea, and for particles with a particle size of 10-20 μm, most of them will be deposited in the mouth.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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