Evaluation of the complex treatment effectiveness of malignant non-organ retroperitoneal tumorson a relapse-free period

¹ Samarkand State Medical Institute, Samarkand, Uzbekistan
² Tashkent State Pedagogical University, Tashkent, Uzbekistan

^* Corresponding author: dr.ulmasov@gmail.com

Abstract

The article delineates the immediate and long-term results of 54 patients with non-organ tumors of the retroperitoneal space who witnesseda number of complex treatments. Tumors of a malignant nature were histologically verified by trepan biopsy in all patients (100%). In the group,liposarcoma was verified in 16 (29.6%) patients, leiomyosarcoma in 17 (31.5%), fibrosarcoma in 9 (16.7%), pleomorphic sarcoma in 8 (14.8%), angiosarcoma in 4 (7 , 4%) patients. Depending on treatment method, patients were stratified into 2 groups - main n = 26 and n = 28. All patients underwent radical surgery after 3 courses of PCT after which they received a course of radiation therapy (ROD-1.8-2Gy). Preoperative chemotherapy before the operation had led to partial tumor regression in 10 (38.5%) patients. 6 (23.0%) patients registered stabilization and progression of the process was observed in 3 (11.5%) patients. The relapse-free period in the main group was set to become 10.2 + 0.4 months while the metastatic-free period was 11.4 + 0.5 months. An integrated approach to the treatment of non-organ retroperitoneal tumors proliferates the average life expectancy of patients as well as the duration of the disease-free and metastatic period.