| Issue |
BIO Web Conf.
Volume 65, 2023
EBWFF 2023 - International Scientific Conference Ecological and Biological Well-Being of Flora and Fauna (Part 2)
|
|
|---|---|---|
| Article Number | 05025 | |
| Number of page(s) | 8 | |
| Section | Preventive Healthcare and Urban Ecology | |
| DOI | https://doi.org/10.1051/bioconf/20236505025 | |
| Published online | 04 September 2023 | |
The effect of "Rheoambrasol" on morphological changes in the liver and kidneys in nitrite methemoglobinemia
1 Fergana Medical Institute of Public Health, 2A, Yangi Turon Street, Fergana, 150100, Uzbekistan
2 Republican Specialized Scientific-Practical Medical Center of Hematology, Tashkent, Uzbekistan
3 Clinic of the Tashkent Medical Academy, Tashkent, Uzbekistan
4 Molecular Genetic Laboratory “GenoTexnologiya”, Tashkent, Uzbekistan
* Corresponding author: mirzaanvar1902@mail.ru
We propose a new drug - "Rheoambrasol" which includes a substance of plant origin (complex compounds of polysaccharide and natural metabolite) non-toxic, environmentally friendly and has wide functional capabilities as a means capable of correcting the consequences of methemoglobinemia, restoring structural and functional properties of cells and preserving their viability. The aim of the work is to study the effect of the new blood substitute "Rheoambrasol" on morphological changes in the liver and kidneys in nitrite methemoglobinemia. The treatment of nitrite methemoglobinemia with rheoambrosol shows complete disappearance of general pathological phenomena both in the liver and kidney tissue. The drug Rheoambrasol containing a natural metabolite of the Krebs cycle in combination with polysaccharides increases the activity of the liver metabolizing function in toxic liver damage. These positive histostructural changes in the liver tissue and in the kidney tissue indicate an increase in the activity of metabolic function of the liver parenchyma and a significant decrease in the toxemia index.
© The Authors, published by EDP Sciences, 2023
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