Morphometric changes in the blood and lymphatic channels during inflammation

¹ Institute of Genetics and Physiology SC MSHE RK, Almaty, 050060, Kazakhstan
² Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan

^* Corresponding author: snabdreshov@mail.ru

Abstract

When the abdominal cavity is inflamed, the lymphatic channel, i.e. the system of lymph vessels and lymph nodes, which play an important role in protecting the body from infections and ensuring proper metabolism, may be affected. Inflammation of the lymphatic channel can lead to its enlargement, soreness and even the formation of purulent foci. The study of morphometric changes in the lymphatic channel during inflammation is an important task for a more detailed understanding of inflammatory processes occurring in the body. The results of our experiments showed that during inflammatory processes of the abdominal cavity there are changes in the blood and lymphatic vessels. Relative volumes of vessels of different types per unit significantly decreased compared to the indicators of the control group. In submucosa and muscularis the morphometry data confirm the fact of arterial vessels spasm, lymphatic vessel reduction and simultaneous persistent venous vessels expansion. In rats with the developed inflammatory process in lymphatic vessels the expansion of lymphatic slits and significant thickening of the wall of large lymphatic vessels was found, which is associated with an increase in the volume of blood plasma, increasing the load on lymphatic vessels as a drainage system of the body.