Camel milk affects serum metabolites by modulating the intestinal microflora

¹ Laboratory of Synthetic Biology, College of Life Science and Technology, Xinjiang University, Urumqi, 830017, People’s Republic of China
² School of Future Technology, Xinjiang University, Urumqi, 830017, People’s Republic of China

^* Corresponding author: yuehaitao@tsinghua.org.cn

Abstract

Gut microbiota significantly influences human health, impacted by factors like diet, genetics, and environment. Camel milk, especially in its fermented form, is rich in nutrients and flee from common allergens, offering both nutritional and therapeutic benefits for centuries. However, comprehensive studies on its effects on gut microbiota and metabolic health are scarce. Our findings demonstrate that fermented camel milk contains beneficial microbes, such as Lactobacillus helveticus and Eubacterium liinosum, which can be transmitted to humans and animals, potentially enhancing gut health and metabolic functions. This study specified that the transportation of microbiome happened both intra- and niter-species and played a principal role in the formation of progeny gut microflora. Specifically, in diabetic rat models, camel whey significantly normalized gut flora and serum metabolites. This underscores camel milk’s potential as a functional food, particularly for managing metabolic disorders.