| Issue |
BIO Web Conf.
Volume 100, 2024
International Scientific Forum “Modern Trends in Sustainable Development of Biological Sciences” (IFBioScFU 2024)
|
|
|---|---|---|
| Article Number | 02014 | |
| Number of page(s) | 5 | |
| Section | Current Issues in Biotechnology, Microbiology, and Bioengineering | |
| DOI | https://doi.org/10.1051/bioconf/202410002014 | |
| Published online | 08 April 2024 | |
Antibacterial activity of freshwater green microalgae from Almaty region
1 Commission on Science and Technology for Sustainable Development in the South (COMSATS), Pakistan
2 Department of Biology, Karadeniz Technical University, 61080, Trabzon, Turkey
3 Department of Biotechnology, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, 050040, Almaty, Kazakhstan
* Corresponding author: huma@comsats.org
The urgent search for new natural bioactive compounds has led to the investigation of freshwater microalgae in the Almaty region for their antibacterial properties. For this purpose, a study was carried out to investigate microalgae cultures from the division of Clorophyta for their potential to produce biologically active compounds (Parachlorella kessleri, Monoraphidium griffithii, Ankistrodesmus falcatus, Nephrochlamys subsolitaria), which also have the potential for wide use in other biotechnological applications. Methanol extracts of 4 strains of microalgae cultures against 11 strains of bacteria were used to evaluate the biological antibacterial activity. Significant antibacterial effects were observed, in particular the methanol extract of P. kessleri showed high activity against B. subtilis, S. aureus and K. pneumoniae; N. subsolitaria showed strong activity against B. subtilis, P. aeruginosa and E. coli. The results of GC/MS analysis confirmed the presence of important bioactive compounds (decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, hexamethylcyclotrisiloxane) in the microalgae extracts. The data obtained play an important role in the development of microalgae-based antibacterial drugs.
© The Authors, published by EDP Sciences, 2024
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