| Issue |
BIO Web Conf.
Volume 100, 2024
International Scientific Forum “Modern Trends in Sustainable Development of Biological Sciences” (IFBioScFU 2024)
|
|
|---|---|---|
| Article Number | 02029 | |
| Number of page(s) | 5 | |
| Section | Current Issues in Biotechnology, Microbiology, and Bioengineering | |
| DOI | https://doi.org/10.1051/bioconf/202410002029 | |
| Published online | 08 April 2024 | |
Assessment of the significance of immunoenzyme test-system for determining antiendotoxic immunity against the endotoxin of gram negative bacteria
1 Tashkent Pharmaceutical Institute
2 Khorezm Region Children’s Multidisciplinary Medical Center, Uzbekistan
The purpose of the study was to determine the specificity and sensitivity of the immunoenzymatic test system that detects antibodies against the antigens of these bacteria in order to evaluate antiendotoxic immunity against GShPB endotoxins. It was found that flat bottom polystyrene solid phase carrier was selected for the proposed experimental test system for the detection of endotoxins of these bacteria by IFA method. The sensitivity of the recommended test system was 75% in colon dysbiosis, 76% in acute tonsillitis, 89% in acute bronchitis, and 95% in urinary tract infections, and the specificity was 5-25%, thus the diagnostic value of this test system it was proved for the first time.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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