| Issue |
BIO Web Conf.
Volume 104, 2024
The 3rd and 4th International Conference on Bioenergy and Environmentally Sustainable Agriculture Technology (ICoN BEAT 2022 and 2023)
|
|
|---|---|---|
| Article Number | 00005 | |
| Number of page(s) | 10 | |
| DOI | https://doi.org/10.1051/bioconf/202410400005 | |
| Published online | 01 May 2024 | |
The Effect of Polyethylene Terephthalate Microplastics on the Growth of Mice
1 University of Muhammadiyah Malang, Malang 6514, East Java, Indonesia
2 Plant Production and Biotechnology – PT Smart Tbk., Bogor 16810, West Java, Indonesia
3 University of Agriculture Peshawar, Pakistan 25130, Khyber Pakhtunkhwa, Pakistan
4 Universitas Islam Madura, Pamekasan 69317, Madura, East Java, Indonesia
5 Merdeka University of Madiun, Madiun 63133, East Java, Indonesia
6 Central Research and Diagnostic Laboratory Satwa Sehat Indonesia, Malang 65146, Indonesia
7 Aura Statistics Consultant, Malang 65141, East Java, Indonesia
8 The State Islamic University of Maulana Malik Ibrahim, Malang 65144, East Java, Indonesia
9 Research Center for Food Technology and Processing (PRTPP), National Research and Innovation Agency (BRIN), Special Region of Yogyakarta 55861, Indonesia
10 Ecological Observation and Wetlands Conservation, Gresik 61177, East Java, Indonesia
11 IPB University, Bogor 16680, West Java, Indonesia
* Corresponding author: meddy@umm.ac.id
Over the course of the previous decade, there has been a growing apprehension regarding the presence of MPs. This concern has arisen because of the detrimental effects of MPs pollution on the well-being of both animals and people. This study explores the potential implications of MPs contamination on mice. This study examined the impact of microplastics on mice by feeding four food experiment; P0 (pellet BR1), P1 (potato from Pujon Farm), P2 (potato mixed 300 µg PET) and P3 (potato mixed 600 µg PET). Body weight, feces weight, and left feed were observed in this study. Food contaminated with microplastics (MPs) has a negative effect on appetite, feces weight and body weight of mice. This process has an impact on reducing the weight of feces, appetite, body weight of mice and weight of mice. It is suspected that MPs in rat digestion increase concentrations of mice corticosterone metabolites and carcass fat, suggesting an adaptation of metabolism to this situation. Another impact is expected the decrease in microbial richness in the intestines of mice, causing a decrease in mice weight and body weight of mice. The high concentration of MPs entering the digestive tract can also reduce the rats’ appetite.
Key words: Contaminated Solanum tuberosum L in vivo study / poison / Rattus norvegicus (Berkenhout, 1769) / toxicity.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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