Drift of antimicrobial resistance of bacterial pathogens of the Moraxella group

Federal State Educational Institution of Higher Professional Education Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Skryabin, 109472 Moscow, Russia

^* Corresponding author: regiotf@yandex.ru

Abstract

The multiple resistance of bacteria to antibiotics leads to a decrease in the effectiveness of treatment methods for bacterial diseases, an increase in morbidity and mortality and, in some cases, to prolonged bacterial transmission. In this regard, the search for new antimicrobial agents and the need to improve veterinary approaches in therapeutic and preventive work with bacterioses is currently a priority task. The study is devoted to the assessment of antibiotic resistance in zoopathogenic moraxella pathogens of infectious bovine keratoconjunctivitis. The article analyzes the drug resistance of topical epizootic strains of Moraxella bovis and M. bovoculi. It was found that since the 1982 study and ending with the own results obtained at the present time, there has been a noticeable increase in the resistance of M. bovis and M. bovoculi to antibiotics. However, a still high level of sensitivity in moraxella is detected for antibiotics of the fluoroquinolone and cephalosporin groups, as well as for ampicillin and benzylpenicillin, the studied bacteria were the most sensitive despite the fact that resistance was recorded for oxacillin and methicillin from the same group.