Comparative characterization of liver morphometric parameters during pregnancy in experimental chronic renal failure

Bukhara State Medical Institute, Bukhara, Uzbekistan

^* Corresponding author: parviz.feruza83@mail.ru

Abstract

Study of morphological and morphometric changes of the liver of pregnant white rats after chronic renal failure. [9]. A study of normal morphological and morphometric parameters of the liver of pregnant white rats. Study of the anatomical parameters of the liver of purebred rats in pregnancy and its reactive changes after experimental chronic renal failure Comparison of pregnancy-related histo-topographic features of the liver of purebred rats in experimental chronic renal failure with parameters of healthy rats; [10]. Comparative classification of morphometric changes in the liver of pregnant rats after correction with Juyzar waters in experimental chronic renal failure.Glomerulopathies: focal glomerulosclerosis, membranous and membranous-proliferative glomerulonephritis, the damage of kidney balls is reduced in the primary order. Due to the alteration of the basal membrane of the glomerulus, increased permeability leads to proteinuria. [17]. Prolonged proteinuria results in decreased albumin in the blood plasma (Hypoalbuminemia). The quality of albumin and globulin changes. A decrease in albumin leads to a decrease in osmotic pressure. The passage of fluid from the blood to the tissue increases. The function of sodium and potassium pumps is disturbed. Swelling develops. At the same time, the reduction of albumin leads to an increase in the synthesis of lipoproteins. [16]. This has an effect on the oncotic pressure. The release of a large amount of lipids in the urine is a sign that the permeability of the glomerular basement membrane has changed.