| Issue |
BIO Web Conf.
Volume 121, 2024
Global Summit on Life Sciences and Bio-Innovation: From Agriculture to Biomedicine (GLSBIA 2024)
|
|
|---|---|---|
| Article Number | 04008 | |
| Number of page(s) | 12 | |
| Section | Frontiers in Genetics and Microbiological Research | |
| DOI | https://doi.org/10.1051/bioconf/202412104008 | |
| Published online | 22 July 2024 | |
PCOS in women with infertility and role of determinant genes of steroid hormones
Bukhara State Medical Institute n.a. Abu Ali ibn Sina, Bukhara, Uzbekistan
* Corresponding author: ixtiyarova7272@mail.ru
We observed 125 women: group 1 - 45 women with primary PCOS and infertility; group 2 - 46 women with infertility and PCOS in preparation for ART; group 3 26 conditionally healthy women. Based on the foregoing, we presented the data of our own studies on the assessment of the state, the genes of steroid hormones (CYP17A1-rs743572, CYP19A1-rs247015) based on the analysis of laboratory data. CY17A1 polymorphism in patients with PCOS, it can be said that the GG mutant genotype was statistically significantly more common in patients compared to the control group. When dividing PCOS patients, they were divided into groups and compared with the control group, MS+ PCOS patients had a lower level of the mutant form (GG) genotype compared to the control group, but in MS- PCOS patients compared to the control group, the mutant gene was determined more.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.