l-Carvone – prediction of potential absorption, distribution, metabolism and excretion

¹ University ”Prof. Assen Zlatarov”, Burgas, Bulgaria
² Department of Chemical Technology, University of Plovdiv, Plovdiv, Bulgaria
³ Department of Technology of Tobacco, Sugar, Vegetable and Essential, University of Food Technologies, Plovdiv, Bulgaria
⁴ Analytical and Physical Chemistry Department, University of Food Technologies, Plovdiv, Bulgaria

^* Corresponding author: ivanz.iliev@abv.bg

Abstract

The compound carvone is a monoterpene oxygen derivative. It is presented by light yellow liquid. These compound characteristic a spicy smell and had a sweet taste. In the carvone observed two enantiomeric forms (S)-(+) and (R)-(-). It is used in perfumery and cosmetics, although it’s considered a potential allergen. It’s also used to flavor food and pharmaceutical products. The scope of these work was to predict different properties of l-carvone as physiochemical and lipophilic, water solubility, pharmacokinetics, drug likeness and pharmaceutical properties of the compound.