| Issue |
BIO Web Conf.
Volume 124, 2024
The 2nd International Conference on Food Science and Bio-medicine (ICFSB 2024)
|
|
|---|---|---|
| Article Number | 01004 | |
| Number of page(s) | 5 | |
| Section | Food Science and Biomolecular Engineering | |
| DOI | https://doi.org/10.1051/bioconf/202412401004 | |
| Published online | 23 August 2024 | |
Research Progress of Paclitaxel Drug Source Solution and Extraction and Separation Technology
1 Belief BioMed Co., Ltd., Building 1, No.389, Jinglian Road, Minhang District, Shanghai China
2 Beijing Lu He International Academy, Beijing 101149 China
a ljrao@sina.com
b xinrong2025@foxmail.com
Taxol, a natural secondary metabolite extracted from the bark of taxus chinensis, is one of the best natural anti-tumor drugs in the past decade and has great medicinal value. However, the content of paclitaxel in plant body is low, the extraction and separation are difficult, and the drug source is short. Based on the review of the literature on paclitaxel, this paper discusses and reviews the solutions of paclitaxel’s drug sources in terms of its synthesis, plant cell culture, endophytic fungi fermentation and synthetic biology. The research progress of paclitaxel extraction and separation technology and the possibility of large-scale industrial production were considered and prospected, which provided a reference for the solution of the drug source problem of paclitaxel and further study.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.