| Issue |
BIO Web Conf.
Volume 174, 2025
2025 7th International Conference on Biotechnology and Biomedicine (ICBB 2025)
|
|
|---|---|---|
| Article Number | 01024 | |
| Number of page(s) | 5 | |
| Section | Advances in Molecular Biology and Genetic Research | |
| DOI | https://doi.org/10.1051/bioconf/202517401024 | |
| Published online | 12 May 2025 | |
Advances in DNA methylation in screening for Lung cancer
First Clinical Medical College, Nanchang University, Nanchang, 330031, China
* Corresponding author’s e-mail: tccunzhihui@163.com
Lung cancer (LC) represents the most life-threatening malignancy in the world today. Currently, low-dose chest computed tomography (LDCT) and tumor markers represent the mainstay for LC screening. However, these screening methods can only detect LC that already formed. Thus there is a need for the development of new tests for LC screening. A substantial body of evidence from scientific research indicates that dysregulated DNA methylation may play a role in the pathogenesis of a variety of diseases, including cancer. Consequently, DNA methylation testing is anticipated to become a screening test for LC. This paper examines the high-throughput detection of DNA methylation in a range of biological specimens, including tissues, blood, and others, which contributed to its potential as a marker for LC screening, recurrence monitoring, and prognosis. Numerous combinations of markers can be constructed to predict LC incidence and prognosis based on the detection of DNA methylation.
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.