| Issue |
BIO Web Conf.
Volume 174, 2025
2025 7th International Conference on Biotechnology and Biomedicine (ICBB 2025)
|
|
|---|---|---|
| Article Number | 03005 | |
| Number of page(s) | 6 | |
| Section | Technologies and Methodologies in Biomedical Research | |
| DOI | https://doi.org/10.1051/bioconf/202517403005 | |
| Published online | 12 May 2025 | |
Metabolomics in Parkinson’s disease biomarker discovery and drug evaluation study
School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, China
* Corresponding author’s e-mail: ray_shield163@163.com
Metabolomics, as a tool for systematically studying metabolites in biological systems, has become a key approach in exploring the pathogenesis of Parkinson’s disease (PD) and evaluating drug efficacy. This article, based on the latest metabolomics research, discusses the discovery process of PD biomarkers, the analysis of related metabolic pathways, and strategies for evaluating drug efficacy. By analyzing the metabolic differences between healthy and PD groups, several key biomarkers were identified, and their potential in PD diagnosis and treatment was explored. Additionally, the combination of metabolomics with organ-on-chip technology provides a new avenue for drug safety evaluation. This study offers important theoretical insights for the early diagnosis of PD and drug evaluation.
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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