| Issue |
BIO Web Conf.
Volume 181, 2025
V International Scientific and Practical Conference “Ensuring Sustainable Development in the Context of Agriculture, Energy, Ecology and Earth Science” (ESDCA 2025)
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|---|---|---|
| Article Number | 01031 | |
| Number of page(s) | 6 | |
| Section | Agriculture | |
| DOI | https://doi.org/10.1051/bioconf/202518101031 | |
| Published online | 19 June 2025 | |
Changes in blood leukogram during the treatment of purulent otitis in rabbits by using different methods
1 Samarkand State University of Veterinary Medicine, Livestock and Biotechnologies, Samarkand, Uzbekistan
2 Samarkand State Medical University, Samarkand, Uzbekistan
* Corresponding author: hkhkniyazov@yandex.ru
The article examines the therapeutic efficacy of various treatment methods in experimentally induced purulent otitis in rabbits. The condition was artificially induced by introducing pure microbial isolates, obtained from the purulent exudates of rabbits with otitis, into the ears of healthy rabbits. It was established that the application of 0.25% levomycetin alcohol, dioxidine, chymotrypsin, hydrocortisone, adrenaline, fluconazole, and cefotaxime-BHF3, in specific doses and sequences, led to a significant reduction in the duration of purulent otitis treatment. Hematological analysis showed an increase in eosinophils, segmented neutrophils, and monocytes, along with a decrease in lymphocytes in the leukogram. Based on the conducted experiments, it was concluded that the effectiveness of the administered drugs could be evaluated through changes in blood parameters. Additionally, no clinical signs of otitis were observed in the treated rabbits.
© The Authors, published by EDP Sciences, 2025
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