| Issue |
BIO Web Conf.
Volume 186, 2025
The 2nd International Seminar on Tropical Bioresources Advancement and Technology (ISOTOBAT 2025)
|
|
|---|---|---|
| Article Number | 01005 | |
| Number of page(s) | 10 | |
| Section | Agriculture, Animal Sciences, Agroforestry, and Agromaritime Innovation | |
| DOI | https://doi.org/10.1051/bioconf/202518601005 | |
| Published online | 22 August 2025 | |
Polymorphism and association of the BGN gene with cholesterol in lamb meat
1 Graduate School of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor 16680, Indonesia
2 Department of Animal Science, Faculty of Fisheries and Animal Science, Universitas Islam Lamongan, Lamongan 62211, Indonesia
3 Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor 16680, Indonesia
4 Department of Animal Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor 16680, Indonesia
5 Faculty of Animal Science, Jambi University, Jambi 36122, Indonesia
* Corresponding author: agunawan@apps.ipb.ac.id
Cholesterol levels in meat serve as an assessment for individuals selecting healthy meat options, correlating with an increased understanding of its importance to health. Biglycan (BGN) is hypothesized to influence cholesterol levels in lamb meat. This research aims to find variations of the BGN gene as potential genetic determinants of cholesterol levels in lambs. A total of 87 rams were analyzed for polymorphism using the PCR-RFLP method. The association between BGN gene polymorphisms and cholesterol in lamb meat was examined using a General Linear Model (GLM). This results from polymorphism by exhibiting two genotypes (GG and CC). A significant association (p < 0.05) was observed between BGN and cholesterol levels in lamb meat. Notably, rams with the GG genotype had significantly lower cholesterol levels when compared to those with the CC genotype. These results indicate that BGN is a good option for genetic selection to lower cholesterol levels in lambs.
© The Authors, published by EDP Sciences, 2025
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