| Issue |
BIO Web Conf.
Volume 223, 2026
The 3rd International Conference on Food Technology and Nutrition (ICFTN 2025)
|
|
|---|---|---|
| Article Number | 06001 | |
| Number of page(s) | 15 | |
| Section | Food Biochemistry | |
| DOI | https://doi.org/10.1051/bioconf/202622306001 | |
| Published online | 25 February 2026 | |
Extraction and Isolation of Active Fraction from Senna multijuga Bark as Antifungal Agents against Ganoderma Boninense
1 Department of Agricultural Product, Faculty of Agriculture, University of Lampung, Lampung - Indonesia 35145
2 Division of Sustainability, Research and Development, PT Sampoerna Agro Tbk, Jakarta - Indonesia 12930
3 Department of Plant Protection, Faculty of Agriculture, University of Lampung, Lampung - Indonesia 35145
* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Ganoderma boninense is a fungus that causes basal stem rot disease in oil palm plants. This fungus disrupts the transport of water and nutrients from the soil, leaf chlorosis, stem decay, fruitlessness, and ultimately death. This study is one of the first to specifically explore the bark of Senna multijuga as a source of antifungal compounds against Ganoderma boninense. Previous studies have focused more on leaf extracts from other Senna species, so the use of S. multijuga bark provides a new contribution to the search for biological agents to control G. boninense. This study aims to extract and isolate the active fraction from S. multijuga bark as antifungal agents against G. boninense. The study was conducted in three stages. The extraction and isolation of the active fraction from S. multijuga bark as antifungal agents against G. boninense, the determination of the chemical composition of the S. multijuga bark, and the antifungal activity of the active fraction against G. boninense in vitro. Based on the GC-MS results for fraction-1 from S. multijuga bark showed the main compounds of 1-hexadecene (5.51%), 1-octadecene (8.29%), hexadecanoid acid (10.46%), 2-ethoxycyclohexanol (5.53%), 9,12-octadecadienoic acid (8.91%), 9,12,15-octadecatrienoic acid (7.70%), 2-hexadecen-1-ol (5.48%), 1-docosene (3.33%), 2-pyridol (6.28%), and calotropenol acetate (6.52%). A concentration of fraction-1 at 1.50 ppm can inhibit the growth of G. boninense (0.32 cm/day), inhibition of G. boninense (67,46%), and produce thin white mycelium that collects in the middle of the medium.
© The Authors, published by EDP Sciences, 2026
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