| Issue |
BIO Web Conf.
Volume 233, 2026
9th International Conference on Advances in Biosciences and Biotechnology: Emerging Innovations in Biomedical and Bioengineering Sciences (ICABB 2026)
|
|
|---|---|---|
| Article Number | 01001 | |
| Number of page(s) | 10 | |
| Section | Biomedical and Health Innovations | |
| DOI | https://doi.org/10.1051/bioconf/202623301001 | |
| Published online | 23 April 2026 | |
Comparative Evaluation of 1,8 cineole on inhibition and migration of Human Ovarian Cancer Cell Lines SKOV3 and PA-1
Department of Biotechnology, Jaypee Institute of Information Technology, Sector-62, Noida, Uttar Pradesh, India 201309
* Corresponding Author Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Ovarian cancer is a leading cause of mortality among gynecological malignancies, primarily due to delayed diagnosis and the limited effectiveness of existing therapeutic strategies. The search for safer and more effective treatment options has led to increasing interest in plant-derived phytocompounds, which exhibit diverse biological activities with comparatively fewer adverse effects. This study evaluates and compares the effects of the phytocompound 1,8- cineole on human ovarian cancer cell lines SKOV3 and PA-1. The anti-cancer activity of 1,8 cineole was evaluated using in vitro cell viability assays, supported by cell migration-based assays to assess changes in cellular behavior following treatment. The results have reported a significant level in reduction of growth and migratory potential upon 1,8 cineole exposure, indicating their ability to interfere with key processes involved in cancer progression
Key words: Anti-proliferative / Cell migration / Ovarian cancer / PA-1 / Phytocompounds / SKOV3
© The Authors, published by EDP Sciences, 2026
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