BIO Web Conf.
Volume 14, 2019The 12th International Conference on the Health Effects of Incorporated Radionuclides (HEIR 2018)
|Number of page(s)||1|
|Section||Biokinetics and Bioaccumulation of Radionuclides: Poster presentation|
|Published online||07 May 2019|
Microdistribution of plutonium in human skeleton. Should we change the ICRP model?
Southern Urals Biophysics Institute, FMBA of Russia
* Corresponding author: firstname.lastname@example.org
Skeleton is one of the major organs of plutonium deposition within the human body. It is well known that plutonium distribution in bone tissue is quite uneven. According to generally accepted model, main fraction of plutonium activity resides on endosteal bone surface and Haversian canal walls. Present study is devoted to analyzing plutonium microdistribution in the thoracic vertebra obtained from a former Mayak PA worker and preserved by SUBI Human Tissue Repository; the analysis was carried out using neutron induced autoradiography.
Obtained results are in sharp contrast with the corresponding values for Leggett’s biokinetic skeletal model recommended by ICRP, especially in case of cortical bone. According to main results of the study, the authors suggest adjusting the parameters of ICRP biokinetic model and to revise dose coefficients for radiation protection purposes.
© The Authors, published by EDP Sciences, 2019
This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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