Physiological parameters of hemostasis in weakened newborn piglets and calves with gamavit injection

Open Access

Table 1.

State of hemostasis in physically impaired newborn calves and piglets against the background of gamavit

Indicators hemostasis	Newborn calves, M±m			Newborn piglets, M±m
Indicators hemostasis	at the beginning of observation, n=48	at the end of the observation, n=48	control group, n=42	at the beginning of observation, n=39	at the end of the observation, n=39	control group, n=35
Platelet aggregation time with ADP, s	26.8±0.12	38.6±0.16	40.6±0.10	27.2±0.14	37.6±0.10	39.1±0.16
Platelet aggregation time with ADP, s	26.8±0.12	p₁<0.01	p<0.01	27.2±0.14	p₁<0.01	p<0.01
Platelet aggregation time with collagen, s	21.3±0.19	30.1±0.22	31.2±0.14	20.2±0.24	29.6±0.17	30.8±0.09
Platelet aggregation time with collagen, s	21.3±0.19	p₁<0.01	p<0.01	20.2±0.24	p₁<0.01	p<0.01
The value of the index of antiplatelet activity of the vascular wall with ADP	1.42±0.17	1.60±0.10	1.68±0.13	1.48±0.19	1.63±0.16	1.66±0.17
	1.42±0.17	p₁<0.01	p<0.01	1.48±0.19	p₁<0.01	p<0.01
The value of the index of antiaggregatory activity of the vascular wall with collagen	1.32±0.07	1.56±0.09	1.60±0.08	1.34±0.11	1.52±0.08	1.58±0.10
	1.32±0.07	p₁<0.01	p<0.01	1.34±0.11	p₁<0.01	p<0.01
Activity antithrombin III, %	86.7±0.14	95.8±0.18	99.8±0.17	85.6±0.10	96.2±0.14	98.6±0.21
Activity antithrombin III, %	86.7±0.14	p₁<0.01	p<0.01	85.6±0.10	p₁<0.01	p<0.01
Value index of anticoagulation activity of the vascular wall	1.16±0.06	1.30±0.05	1.33±0.07	1.15±0.09	1.29±0.04	1.30±0.05
	1.16±0.06	p₁<0.01	p<0.01	1.15±0.09	p₁<0.01	p<0.01
Time spontaneous euglobulin lysis time, min	236.0±0.42	197.2±0.37	186.1±0.41	227.5±0.54	189.7±0.32	183.1±0.32
Time spontaneous euglobulin lysis time, min	236.0±0.42	p₁<0.01	p<0.01	227.5±0.54	p₁<0.01	p<0.01
Value index of fibrinolytic activity of the vascular wall	1.25±0.06	1.39±0.11	1.42±0.16	1.23±0.09	1.37±0.07	1.39±0.12
Value index of fibrinolytic activity of the vascular wall	1.25±0.06	p₁<0.01	p<0.01	1.23±0.09	p₁<0.01	p<0.01
Activated partial thromboplastin time, s Prothrombin time, s	31.6±0.16	38.2±0.21	40.2±0.30	32.0±0.28	38.8±0.19	39.2±0.24
	31.6±0.16	p₁<0.01	p<0.01	32.0±0.28	p₁<0.01	p<0.01
Activated partial thromboplastin time, s Prothrombin time, s	14.1±0.19	17.2±0.20	17.9±0.18	14.3±0.15	17.0±0.24	17.6±0.16
	14.1±0.19	p₁<0.01	p<0.01	14.3±0.15	p₁<0.01	p<0.01
Thrombin time, s	16.2±0.29	18.2±0.21	18.6±0.20	16.1±0.31	17.5±0.18	18.0±0.25
Thrombin time, s	16.2±0.29	p₁<0.01	p<0.01	16.1±0.31	p₁<0.01	p<0.01

Note: p – significance of differences in outcome and control, p₁ – significance of differences in the dynamics of indicators during correction.

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