Bovine fetal tissue extracts as an alternative to fetal serum for in vitro reproduction of viruses

Open Access

Table 3.

Titers of IR and PI-3 viruses during reproduction of LEK cell culture

Growth‐stimulating component of culture medium	Virus titre, lg Tissue cytopathic dose 50/ml
	IR	PI‐3
Tissue extracts of:
muscles	6.2 + 0.1^*	4.7 + 0.2^*
liver	4.7 + 0.2^**	4.0 + 0.2^***
kidneys	4.7 + 0.3^**	4.2 + 0.1^***
Fetal bovine blood serum	7.0 + 0.2	7.0 + 0.2
Control ‐ bovine blood serum	6.7 + 0.1	6.5 + 0.3

Note: *, **, *** - the levels of significance of differences relative to control (p), respectively <0.05; <0.01 and <0.01.

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