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All issues Volume 228 (2026) BIO Web Conf., 228 (2026) 06001 References
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Issue
BIO Web Conf.
Volume 228, 2026
Biospectrum 2025: International Conference on Biotechnology and Biological Science
Article Number 06001
Number of page(s) 9
Section Medical Biotechnology II
DOI https://doi.org/10.1051/bioconf/202622806001
Published online 11 March 2026
  • Robinson TP, Bu DP, Carrique-Mas J, et al. Trans R Soc Trop Med Hyg. 2016;110(7):377–380. [Google Scholar]
  • Hall-Stoodley L, Costerton JW, Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol. 2004;2(2):95–108. [Google Scholar]
  • Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science. 1999;284(5418):1318–22. [CrossRef] [PubMed] [Google Scholar]
  • Stewart PS, Costerton JW. Antibiotic resistance of bacteria in biofilms. Lancet. 2001;358(9276):135–8. [Google Scholar]
  • Flemming H-C, Wingender J. The biofilm matrix. Nat Rev Microbiol. 2010;8(9):623–33. [Google Scholar]
  • Flemming H-C, Wingender J, Szewzyk U, et al. Biofilms: an emergent form of bacterial life. Nat Rev Microbiol. 2016;14(9):563–75. [Google Scholar]
  • Stewart PS, Franklin MJ. Physiological heterogeneity in biofilms. Nat Rev Microbiol. 2008;6(3):199–210. [Google Scholar]
  • Bjarnsholt T. The role of bacterial biofilms in chronic infections. APMIS Suppl. 2013;(136):1–51. [Google Scholar]
  • Petrova OE, Sauer K. Escaping the biofilm in more than one way: desorption, detachment or dispersion. Curr Opin Microbiol. 2016;30:67–78. [Google Scholar]
  • Chiang WC, Nilsson M, Jensen PØ, et al. Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Pathog Dis. 2013;69(2):158–64. [Google Scholar]
  • Lewis K. Persister cells, dormancy and infectious disease. Nat Rev Microbiol. 2007;5(1):48–56. [Google Scholar]
  • Keren I, Kaldalu N, Spoering A, et al. Persister cells and tolerance to antimicrobials. FEMS Microbiol Lett. 2004;230(1):13–8. [Google Scholar]
  • Winstanley C, O’Brien S, Brockhurst MA. Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections. Trends Microbiol. 2016;24(5):327–37. [Google Scholar]
  • Römling U, Galperin MY, Gomelsky M. Cyclic di-GP: the first 25 years of a universal bacterial second messenger. Microbiol Mol Biol Rev. 2013;77(1):1–52. [Google Scholar]
  • Hentzer M, Givskov M. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest. 2003;112(9):1300–7. [Google Scholar]
  • Nadell CD, Xavier JB, Levin SA, Foster KR. The evolution of quorum sensing in bacterial biofilms. PLoS Biol. 2008;6(1):e14. [Google Scholar]
  • Fleming D, Rumbaugh KP. Approaches to dispersing medical biofilms. Microorganisms. 2017;5(2):15. [Google Scholar]
  • Poole K. Efflux-mediated antimicrobial resistance. J Antimicrob Chemother. 2005;56(1):20–51. [Google Scholar]
  • Conlon BP. Persister cells in biomedicine. Curr Biol. 2014;24(14):R654–R657. [Google Scholar]
  • Madsen JS, Burmølle M, Hansen LH, Sørensen SJ. The interconnection between biofilm formation and horizontal gene transfer. FEMS Immunol Med Microbiol. 2012;65(2):183–95. [Google Scholar]
  • Hausner M, Wuertz S. High rates of conjugation in bacterial biofilms as determined by quantitative in situ analysis. Appl Environ Microbiol. 1999;65(8):3710–3. [Google Scholar]
  • Molin S, Tolker-Nielsen T. Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilization of the biofilm structure. Curr Opin Biotechnol. 2003;14(3):255–61. [Google Scholar]
  • Domingues S, Harms K, Fricke WF, et al. Natural transformation facilitates transfer of transposons, integrons and gene cassettes among bacteria. Nucleic Acids Res. 2012;40(18):e101. [Google Scholar]
  • Andersson DI, Hughes D. Microbiological effects of sublethal levels of antibiotics. Nat Rev Microbiol. 2014;12(7):465–78. [Google Scholar]
  • Donlan RM. Biofilms and device-associated infections. Emerg Infect Dis. 2001;7(2):277–81. [Google Scholar]
  • Arciola CR, Campoccia D, Montanaro L. Implant infections: adhesion, biofilm formation and immune evasion. Nat Rev Microbiol. 2018;16(7):397–409. [Google Scholar]
  • Percival SL, Suleman L, Vuotto C, Donelli G. Healthcare-associated infections, medical devices and biofilms: risk, tolerance and control. J Med Microbiol. 2015;64(4):323–34. [Google Scholar]
  • Malone M, Bjarnsholt T, McBain AJ, et al. The prevalence of biofilms in chronic wounds: a systematic review. Adv Wound Care. 2017;6(12):403–19. [Google Scholar]
  • Hauser AR, Jain M, Bar-Meir M, McColley SA. Clinical significance of microbial infection and biofilms in cystic fibrosis. Clin Microbiol Rev. 2011;24(1):29–70. [Google Scholar]
  • Wingender J, Flemming H-C. Biofilms in drinking water and their role as reservoir for pathogens. Int J Hyg Environ Health. 2011;214(6):417–23. [CrossRef] [PubMed] [Google Scholar]
  • Walker JT, Bradshaw DJ, Finney M, et al. Microbiological evaluation of dental unit water systems. J Hosp Infect. 2000;46(2):148–52. [Google Scholar]
  • Rickard AH, Gilbert P, High NJ, et al. Bacterial coaggregation in mixed-culture biofilms. J Appl Microbiol. 2003;95(5):744–55. [Google Scholar]
  • Bridier A, Sanchez-Vizuete P, Guilbaud M, et al. Biofilm-associated persistence of food-borne pathogens. Food Microbiol. 2015;45(Pt B):167–78. [Google Scholar]
  • Fagerlund A, Møretrø T, Heir E, et al. Cleaning and disinfecting agents can select for antibiotic resistance. Microbiology. 2016;162(10):1737–43. [Google Scholar]
  • EFSA BIOHAZ Panel. Scientific opinion on the role of biofilms in persistent Listeria monocytogenes contamination of food processing environments. EFSA Journal. 2018;16(7):5305. [Google Scholar]
  • Defoirdt T, Sorgeloos P, Bossier P. Alternatives to antibiotics for the control of bacterial disease in aquaculture. Curr Opin Microbiol. 2011;14(3):251–8. [Google Scholar]
  • Romalde JL, Toranzo AE. Bacterial infections in marine fish: biofilm involvement and control. Int Microbiol. 2022;25:541–55. [Google Scholar]
  • Simões M, Simões LC, Vieira MJ. A review of current and emergent biofilm control strategies. LWT – Food Sci Technol. 2010;43(4):573–83. [Google Scholar]
  • Ferreira V, Wiedmann M, Teixeira P, Stasiewicz MJ. Listeria monocytogenes persistence in food-associated environments: epidemiology, strain characteristics, and implications for public health. J Food Prot. 2014;77(1):150–70. [Google Scholar]
  • Ramey BE, et al. Annu Rev Phytopathol. 2004;42:117–1 [Google Scholar]
  • Rizzo L, Manaia CM, Merlin C, et al. Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review. Sci Total Environ. 2013;447:345–60. [NASA ADS] [CrossRef] [PubMed] [Google Scholar]
  • Michael I, Rizzo L, McArdell CS, et al. Urban wastewater treatment plants: advanced treatment to reduce residual antibiotics? Environ Int. 2013;61:127–51. [Google Scholar]
  • Ju F, Li B, Ma L, et al. Antibiotic resistance genes and bacterial communities in urban lakes: linkages between ARGs and microbial community at assemble and species levels. ISME J. 2016;10(7):164–75. [Google Scholar]
  • Bengtsson-Palme J, Larsson DGJ. Concentrations of antibiotics predicted to select for resistant bacteria: proposed limits for environmental regulation. Environ Int. 2016;86:140–9. [Google Scholar]
  • Manaia CM. Assessing the risk of antibiotic resistance transmission from the environment to humans: non-direct proportionality between abundance and risk. Trends Microbiol. 2017;25(3):173–81. [Google Scholar]
  • Prest EI, Hammes F, van Loosdrecht MCM, Vrouwenvelder JS. Biological stability of drinking water: controlling factors, methods, and challenges. Front Microbiol. 2016;7:45. [Google Scholar]
  • Proctor CR, Hammes F. Drinking water microbiology—from measurement to management. Curr Opin Biotechnol. 2015;33:87–94. [CrossRef] [PubMed] [Google Scholar]
  • Douterelo I, Boxall JB, Deines P, et al. Methodological approaches for studying the microbial ecology of drinking water distribution systems. Water Res. 2014;65:134–56. [Google Scholar]
  • Pal C, Asiani K, Arya S, et al. Metal resistance and antibiotic resistance co-select in natural environments. Nat Commun. 2017;8:15503. [Google Scholar]
  • Wales AD, Davies RH. Co-selection of resistance to antibiotics, biocides and heavy metals, and its relevance to foodborne pathogens. Antibiotics (Basel). 2015;4(4):567–604. [Google Scholar]
  • O’Toole GA. Microtiter dish biofilm formation assay. J Vis Exp. 2011;(47):e2437. [Google Scholar]
  • Azeredo J, Azevedo NF, Briandet R, et al. Critical review on biofilm methods. Crit Rev Microbiol. 2017;43(3):313–51. [Google Scholar]
  • Ceri H, Olson ME, Stremick C, et al. The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms. J Clin Microbiol. 1999;37(6):1771–6. [Google Scholar]
  • Neu TR, Lawrence JR. Innovative techniques, sensors, and approaches for imaging biofilms at different scales. Trends Microbiol. 2015;23(4):233–42. [Google Scholar]
  • Su J-Q, An X-L, Li B, et al. Metagenomics of urban sewage identifies an extensively shared antibiotic resistome across human populations. Nat Commun. 2017;8:233. [Google Scholar]
  • Stalder T, Press MO, Sullivan S, et al. Linking the resistome and plasmidome to the microbiome. ISME J. 2019;13(10):2437–46. [Google Scholar]
  • World Health Organization. Global Action Plan on Antimicrobial Resistance. Geneva: WHO; 2015. [Google Scholar]
  • International standards (CLSI/EUCAST) discussion papers on biofilm susceptibility testing. CLSI/EUCAST documents; various years. [Google Scholar]
  • Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report. Geneva: WHO; 2022. [Google Scholar]
  • Epstein AK, Wong T-S, Belisle RA, Boggs EM, Aizenberg J. Liquid-infused structured surfaces with exceptional anti-biofouling performance. Proc Natl Acad Sci USA. 2012;109(33):13182–7. [Google Scholar]
  • Reddy ST, Swartz MA. A biomimetic model of interstitial flow and its effects on extracellular matrix deposition. Biophys J. 2007;93(7):230–41. [Google Scholar]
  • Leng C, Sun S, Zhang K, Jiang S. Zwitterionic surfaces for antifouling: mechanisms and applications. Acta Biomater. 2016;40:6–16. [Google Scholar]
  • Hentzer M, Riedel K, Rasmussen TB, et al. Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology. 2002;148(Pt 1):87–102. [Google Scholar]
  • Tetz GV, Artemenko NK, Tetz VV. Effect of DNase and antibiotics on biofilm characteristics. Antimicrob Agents Chemother. 2009;53(3):1204–9. [Google Scholar]
  • Qian Z, Sagers RD, Pitt WG. The effect of ultrasonic frequency upon enhanced killing of Pseudomonas aeruginosa biofilms. Ann Biomed Eng. 1999;27(1):132–8. [Google Scholar]
  • Dai T, Huang Y-Y, Hamblin MR. Photodynamic therapy for localized infections—state of the art. Photodiagnosis Photodyn Ther. 2009;6(3–4):170–88. [Google Scholar]
  • Barraud N, Buson A, Jarolimek W, Rice SA. Mannitol enhances antibiotic sensitivity of Pseudomonas aeruginosa biofilms by reversing metabolic states. PLoS One. 2013;8(12):e84220. [Google Scholar]
  • Conlon BP, Nakayasu ES, Fleck LE, et al. Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature. 2013;503(7476):365–70. [Google Scholar]
  • LaSarre B, Federle MJ. Exploiting quorum sensing to confuse bacterial pathogens. Microbiol Mol Biol Rev. 2013;77(1):73–111. [Google Scholar]
  • Abedon ST. Bacteriophage exploitation of bacterial biofilms: phage preference and penetration. J Bacteriol. 2011;193(15):3730–6. [Google Scholar]
  • Chan BK, Abedon ST, Loc-Carrillo C. Phage cocktails and the future of phage therapy. Future Microbiol. 2013;8(6):769–83. [Google Scholar]
  • Fischetti VA. Bacteriophage endolysins: a novel anti-infective paradigm. Clin Microbiol Rev. 2005;18(4):544–61. [Google Scholar]
  • Defoirdt T. Quorum-sensing systems as targets for antivirulence therapy in Vibrio infections. Int J Mol Sci. 2018;19(7):2067. [Google Scholar]
  • Lebeaux D, Ghigo J-M, Beloin C. Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance. Microbiol Mol Biol Rev. 2014;78(3):510–43 [Google Scholar]

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