Open Access
Issue
BIO Web Conf.
Volume 232, 2026
2026 16th International Conference on Bioscience, Biochemistry and Bioinformatics (ICBBB 2026)
Article Number 01005
Number of page(s) 46
Section Bioinformatics Algorithms and Advanced Omics Data Analysis
DOI https://doi.org/10.1051/bioconf/202623201005
Published online 24 April 2026
  • L. McInnes, J. Healy, and J. Melville, "UMAP: Uniform Manifold Approximation and Projection for Dimensionality reduction," arXiv, 2018, doi: 10.48550/arxiv.1802.03426. [Google Scholar]
  • C. Trapnell et al., "The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells," Nat. Biotechnol., vol. 32, no. 4, pp. 381–386, 2014, doi: 10.1038/nbt.2859. [Google Scholar]
  • M. Tang et al., "Evaluating single-cell cluster stability using the Jaccard similarity index," Bioinformatics, vol. 37, no. 15, pp. 2212–2214, 2020, doi: 10.1093/bioinformatics/btaa956. [Google Scholar]
  • C. N. Heiser and K. S. Lau, "A Quantitative Framework for Evaluating Single-Cell Data Structure Preservation by Dimensionality Reduction Techniques," Cell Rep., vol. 31, no. 5, p. 107576, 2020, doi: 10.1016/j.celrep.2020.107576. [Google Scholar]
  • X. Liu et al., "A comparison framework and guideline of clustering methods for mass cytometry data," Genome Biol, vol. 20, no. 1, p. 297, 2019, doi: 10.1186/s13059-019-1917-7. [Google Scholar]
  • M. Chatzou, E. W., P. Di, Gascuel, and Notredame, "Generalized Bootstrap Supports for Phylogenetic Analyses of Protein Sequences Incorporating Alignment Uncertainty," Systematic Biology, 2018, doi: 10.1093/sysbio/syx096. [Google Scholar]
  • J. Cao et al., "Comprehensive single-cell transcriptional profiling of a multicellular organism," Science, vol. 357, no. 6352, pp. 661–667, 2017, doi: 10.1126/science.aam8940. [Google Scholar]
  • J. S. Packer et al., "A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution," Science, vol. 365, no. 6459, 2019, doi: 10.1126/science.aax1971. [Google Scholar]
  • D. Balboa et al., "Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells," Nat. Biotechnol., vol. 40, no. 7, pp. 1042–1055, 2022, doi: 10.1038/s41587-022-01219-z. [Google Scholar]
  • E. Z. Macosko et al., "Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets," Cell, vol. 161, no. 5, pp. 1202–1214, 2015, doi: 10.1016/j.cell.2015.05.002. [Google Scholar]
  • M. Ximerakis et al., "Single-cell transcriptomic profiling of the aging mouse brain," Nat. Neurosci., vol. 22, no. 10, pp. 1696–1708, 2019, doi: 10.1038/s41593-019-0491-3. [Google Scholar]
  • D. F. Robinson and L. R. Foulds, "Comparison of phylogenetic trees," Math. Biosci., vol. 53, no. 1-2, pp. 131–147, 1981, doi: 10.1016/0025-5564(81)90043-2. [Google Scholar]
  • C. D. Michener and R. R. Sokal, "A QUANTITATIVE APPROACH TO A PROBLEM IN CLASSIFICATION!," Evol. Int. J. Org. Evol., vol. 11, no. 2, pp. 130–162, 1957, doi: 10.1111/j.1558-5646.1957.tb02884.x. [Google Scholar]
  • T. Caliñski and J. Harabasz, "A dendrite method for cluster analysis," Commun. Stat., vol. 3, no. 1, pp. 1–27, 1974, doi: 10.1080/03610927408827101. [Google Scholar]
  • D. L. Davies and D. W. Bouldin, "A cluster separation measure.," IEEE Trans. pattern Anal. Mach. Intell., vol. 1, no. 2, pp. 224–7, 1979. [Google Scholar]
  • X. L. Xie and G. Beni, "A validity measure for fuzzy clustering," IEEE Trans. Pattern Anal. Mach. Intell., vol. 13, no. 8, pp. 841–847, 2024, doi: 10.1109/34.85677. [Google Scholar]
  • W. Kobak and P. Berens, "The art of using t-SNE for single-cell transcriptomics," Nat. Commun., vol. 10, no. 1, p. 5416, 2019. [Google Scholar]
  • B. Becht et al., "Dimensionality reduction for visualizing single-cell data using UMAP," Nat. Biotechnol., vol. 39, no. 12, pp. 1480–1490, 2021. [Google Scholar]

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