| Issue |
BIO Web Conf.
Volume 22, 2020
International Conference “Longevity Interventions 2020” (ICLI 2020)
|
|
|---|---|---|
| Article Number | 01003 | |
| Number of page(s) | 5 | |
| Section | Problems of Gerontology and Geriatrics | |
| DOI | https://doi.org/10.1051/bioconf/20202201003 | |
| Published online | 06 July 2020 | |
Cytological features of buccal epithelium in patients of various ages
1
Ural State Medical University, Department of Therapeutic Dentistry and Propaedeutics of Dental Diseases, 620028, Repina street, 3, Ekaterinburg, Russian Federation
2
Ural State Medical University, Central Research Laboratory, 620028, Repina street, 3, Ekaterinburg, Russian Federation
3
Ural State Medical University, student, 620028, Repina street, 3, Ekaterinburg, Russian Federation
* Corresponding author: vanevs@mail.ru
The article describes the potential of buccal cells investigations. The authors presented buccal epithelium application in noninvasive diagnosis of early human aging; identified common cytological features of buccal epithelium for different ages; revealed the accumulation of cytogenetic abnormalities (epithelial cells with micronuclei, protrusions of the nucleus) and degenerative-dystrophic changes (perinuclear vacuole, condensed chromatin, karyorexis, karyolysis) with age. These findings reflect the predominance of apoptosis over reparation in the process of aging.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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