| Issue |
BIO Web Conf.
Volume 24, 2020
International Conferences “Plant Diversity: Status, Trends, Conservation Concept” 2020
|
|
|---|---|---|
| Article Number | 00051 | |
| Number of page(s) | 6 | |
| DOI | https://doi.org/10.1051/bioconf/20202400051 | |
| Published online | 21 September 2020 | |
Antiviral activity of Siberian wild and cultivated plants
1 State Research Center of Virology and Biotechnology VECTOR, w.v. Koltsovo, Novosibirsk region, 630559, Russia
2 Central Siberian Botanical Gardens SB RAS, 630090 ul. Zolotodalinskaya, 101, Novosibirsk, Russia
* Corresponding author: mazurkova@vector.nsc.ru
The article presents data on the antiviral activity of ethanol and aqueous extracts isolated from the herb plants Dracocephalum nutans, Glechoma hederacea, Melissa officinalis, Berteroa incana, Aegopodium podagraria, and Veronica longifolia against the A/Aichi/2/68 (H3N2) and A/chicken/ Kurgan/05/2005 (H5N1) subtypes of influenza A virus (IAV) in MDCK cell culture. It was found that the ethanol extracts of Glechoma hederacea, Berteroa incana, and Aegopodium podagraria have the antiviral activity in vitro in MDCK cell culture against H3N2 subtype of IAV. The aqueous extracts of Glechoma hederacea, Melissa officinalis, Aegopodium podagraria, and Veronica longifolia and ethanol extracts of Berteroa incana and Veronica longifolia are active against H5N1 subtype of IAV. None of the extracts of Dracocephalum nutans showed significant activity against the studied subtypes. The greatest efficiency was shown by the ethanol extract of Aegopodium podagraria against the H5N1 subtype and aqueous extracts from Glechoma hederacea and Melissa officinalis.against the H3N2 subtype. The ethanol extract of Berteroa incana has a high activity against both IAV subtypes, which makes this sample the most promising for creating new drugs for the prevention and treatment of influenza virus.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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