| Issue |
BIO Web Conf.
Volume 30, 2021
II International Symposium “Innovations in Life Sciences” (ILS 2020)
|
|
|---|---|---|
| Article Number | 04007 | |
| Number of page(s) | 4 | |
| Section | Ecological Questions, Environmental Issues and Environmental Education in Modern World | |
| DOI | https://doi.org/10.1051/bioconf/20213004007 | |
| Published online | 22 April 2021 | |
Cytokinetic parameters of erythropoiesis under normal health conditions and during the development of acute lymphoblastic and acute myeloblastic leukemia
1
Department of Biology, Belgorod State National Research University, Belgorod, Russia
2
Department of Biochemistry, Institute of Medicine, Belgorod State National Research University, Belgorod, Russia
* Corresponding author: seliverstov.evgeniy.s@gmail.com
The article presents the application of the method for determining the quantitative parameters of erythropoiesis to patients with acute leukemia. The objective of the work is an investigation of erythropoiesis cytokinetic parameters under the normal health conditions and during the development of the acute lymphoblastic leukemia and the acute myeloblastic leukemia. It was found that the distribution of reticulocytes shifts towards an increase of immature reticulocyte fraction while the ratio between maturing and immature cells remains unchanged. The method presented can be used in clinical diagnostic and scientific research of bone marrow hematopoietic activity.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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