| Issue |
BIO Web Conf.
Volume 31, 2021
VI International Scientific Conference “Problems of Industrial Botany of Industrially Developed Regions” 2021
|
|
|---|---|---|
| Article Number | 00018 | |
| Number of page(s) | 3 | |
| DOI | https://doi.org/10.1051/bioconf/20213100018 | |
| Published online | 13 August 2021 | |
White phosphorus genotoxicity
1 Institute of Power Engineering and Advanced Technologies, FRC Kazan Scientific Center, Russian Academy of Sciences
2 A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences
3 Kazan (Volga region) federal university, Kazan
* Corresponding author: mindubaev-az@yandex.ru
The genotoxicity of white phosphorus was previously evaluated using the Ames test, which demonstrated the absence of toxicity. However, with all the advantages of this method, the use of the Ames test has some shortfallsin assessing genotoxicity. For this purpose, a series of supplementary tests wereconducted, including the SOS-lux test for DNA damaging activity. In the present work,the SOS-lux test confirmed the genotoxicity of white phosphorus. Based on a review of the literature, our results denote a first report on the genotoxic properties of white phosphorus. Allium test showed the mitotoxic effect of white phosphorus on eukaryotic cells.
© The Authors, published by EDP Sciences, 2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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