| Issue |
BIO Web Conf.
Volume 38, 2021
Northern Asia Plant Diversity: Current Trends in Research and Conservation 2021
|
|
|---|---|---|
| Article Number | 00073 | |
| Number of page(s) | 7 | |
| DOI | https://doi.org/10.1051/bioconf/20213800073 | |
| Published online | 28 October 2021 | |
Cacalia hastata L.: anti-influenza activity and phytochemical characteristics of extracts
1
Central Siberian Botanical Garden SB RAS, 630090 Novosibirsk, Russia
2
State Scientific Center of Virology and Biotechnology VECTOR, 630559 Koltsovo, Russia
3
Siberian Botanical Garden at Tomsk State University, 634050 Tomsk, Russia
* Corresponding author: irevlob@ngs.ru
This is the first study to assess antiviral activity against human influenza virus A/Aichi/2/68 and bird influenza virus A/chicken/Kurgan/05/2005 and phytochemical characteristics of an ethanol extract of Cacalia hastata L. from wild populations growing in the vicinity of Tomsk, Russia (mixed forest). A log10 neutralization index—an indicator of inhibition of virus replication by the extract from C. hastata leaves—was ≤2 lg for each influenza virus. The extract reduced the infectivity of the human influenza virus by 1.5-fold and that of the avian influenza virus by 1.7-fold. The phytochemical characterization of C. hastata (its various organs) showed that the largest amount of the tested biologically active substances is present in leaves and rhizomes.
© The Authors, published by EDP Sciences, 2021
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