Vermiculax drug effect on blood parameters, immune response, calcium and phosphorus, and weight of laying hens

¹ Department of Bioecology and Physiology of Farm Animals, Samara State Agrarian University”, 2, Uchebnaya St., Kinel, urban-type settlement Ust-Kinelsky, Samara Region, 446442, Russian Federation
² Department of Non-Infectious Animal Diseases, Orenburg State Agrarian University, 18, Chelyuskintsev St., Orenburg, 460014, Russian Federation

^* Corresponding author: meod.adir@yandex.ru

Abstract

This paper presents the experiment on 160 laying hens of the white Leghorn breed divided into 4 groups. Group I (taken as a control group) was given a basic diet (OR). Group II had OR + Vermiculax at a dosage of 30 mg per 1 kg of the laying hen weight. Group III had OR + Vermiculax at a dosage of 37 mg per 1 kg of the laying hen weight. Group IV consumed OR + Vermiculax at a dosage of 44 mg per 1 kg of the laying hen weight. According to the results of the study, we came to the following conclusions. The drug Vermiculax increases the content of erythrocytes (by 21.45%) and hemoglobin (by 4.94%), which indicates the prevention of anemia, increases the index of total protein by 30.57%, calcium by 0.7% and inorganic phosphorus in the blood by 4.16%. Thus, it affects phagocytic processes, increases the immune response and absorption processes; increases the activity of macrophages and affects the process of degranulation of polymorphonuclear neutrophils, which in turn increases lysozyme activity by 3.9%. This is a sign of strengthening the natural antibacterial barrier. There is an increase in the retention of calcium in the body by 115.32% and phosphorus by 107.94% (on the 30th day of the study). In addition, increased retention of calcium by 8.3% and phosphorus by 8.5% (on the 180th day of the study) was observed. There is an increase in the deposition of calcium in the body by 132.8% and phosphorus by 133.45% (on the 30th day of the study), and increased retention of calcium by 66.36% and phosphorus by 66.4% (on the 180th day of the study). There is a high dynamic in weight gain by the second month of the study (increased by 21.88%), as well as a decrease in the level of feed consumption per weight gain of 1 kilogram by 13.33%.