BIO Web Conf.
Volume 59, 20232023 5th International Conference on Biotechnology and Biomedicine (ICBB 2023)
|Number of page(s)||10|
|Section||Precision Medicine and Drug Development and Preparation|
|Published online||08 May 2023|
Etiology and Treatment of Anxiety
Torrey Pines High School, 3710 Del Mar Heights Rd, San Diego, CA 92130, United States
There is still much debate about the etiology and remedies of anxiety disorders. Summarizing the current research results will facilitate a deeper understanding of anxiety disorders and uncover suitable treatments. Environmental changes, childhood trauma or physical abuse, and a Mediterranean diet or the microbiome were strongly associated with disease development. Also, the PDE4B gene, other essential loci, and 274 genes' interaction with the environment could potentially cause anxiety. Molecules such as the brain receptor GPR158, MicroRNA-137, and the interleukin-17a (IL-17a) showed increased anxiety behaviors. Psychological therapy, such as cognitive behavioral treatment, mindfulness-based cognitive therapy, and internet-delivered behavioral therapy, effectively reduces anxiety. Diazepam and clonazepam, secondary benzodiazepine treatments, showed shortcomings, for example, the former lack of cognitive recovery. Furthermore, SSRIs, including sertraline, fluoxetine, and paroxetine, and SNRIs like venlafaxine or duloxetine, had good efficacy and high tolerability. Animal-assisted intervention, cannabidiol, molecule therapeutics, and many novel approaches in different systems were also proved to be beneficial in decreasing anxiety symptoms. More evidence from studies and reviews is needed to support these findings.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.