| Issue |
BIO Web Conf.
Volume 59, 2023
2023 5th International Conference on Biotechnology and Biomedicine (ICBB 2023)
|
|
|---|---|---|
| Article Number | 03003 | |
| Number of page(s) | 6 | |
| Section | Clinical Trials and Medical Device Monitoring | |
| DOI | https://doi.org/10.1051/bioconf/20235903003 | |
| Published online | 08 May 2023 | |
Research on the Physiological Factors of Cardiac Regeneration
Jinan No.3 High School of Shandong, Jinan, ShanDong Province, 250001, China
* Corresponding author’s e-mail: 750034934@qq.com
The heart is one of the most important organs in mammals. When cardiovascular disease occurs, such as myocardial infarction, many cardiac myocytes die due to hypoxia, leading to heart failure. The ability of adult mammalian cardiomyocytes to proliferate gradually decreases during development. Therefore, when the heart is damaged, it cannot be repaired by the natural division and regeneration of cardiomyocytes, which in turn leads to impaired heart function. Therefore, it is particularly important to improve the proliferative capacity of cardiomyocytes during the treatment of cardiac diseases. Here, we summarize the effects of different factors such as environmental oxygen, energy metabolism, extracellular matrix, nervous system and immune response on cardiomyocyte proliferation and cardiac regeneration with the aim of providing a theoretical basis and potential directions for the treatment of heart disease.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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