| Issue |
BIO Web Conf.
Volume 60, 2023
2022 4th International Conference on Biotechnology and Food Science (BFS 2022)
|
|
|---|---|---|
| Article Number | 01010 | |
| Number of page(s) | 4 | |
| Section | Biochemical Application and Genetic Engineering | |
| DOI | https://doi.org/10.1051/bioconf/20236001010 | |
| Published online | 11 May 2023 | |
Recombination of Goose Parvovirus VP3 Gene and Goose Interferon Ɣ Gene from Fowlpox Virus Immune Protection and Its Mechanism
Laboratory for Animal Molecular Virology, Department of Veterinary Medicine, Agriculture College, Yanbian University, Yanji, China
* Corresponding author: gaoxu@ybu.edu.cn
Gosling plague (GP) is caused by goose parvovirus (GPV) gosling acute, subacute, and septic infectious diseases, commonly known as gosling plague. At present, the prevention and control of GP at home and abroad mainly adopts the method of immunizing female geese with attenuated vaccine. Goslings can be immunized, but there are still the phenomenon of dispersive virus and virulence reverse. It, therefore, is urgent to develop a new safe and effective vaccine. The recombinant avian pox virus vaccines rFPV-GoIFNγ, rFPV-GPV-VP3 and rFPV-GoIFNγ-VP3 were used to monitor their antibody levels and evaluate the protective mechanism of the vaccine in this study. This study lays a foundation for further in vivo testing of recombinant avian pox virus vaccine for goose parvovirus and provides a reference for the development of recombinant avian pox virus vaccine for other avian infectious diseases.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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