BIO Web Conf.
Volume 84, 2024International Scientific and Practical Conference “Development and Modern Problems of Aquaculture” (AQUACULTURE 2023)
|Number of page(s)
|Theoretical Medicine and Bioethics
|05 January 2024
Role of IL-1β, Prolactin and DHEA in men Patients Infected with Toxoplasmosis
1 Wasit University, Department of Biology, Al Kūt, Iraq
2 University of Kufa, Department of Biology, Kufa, Najaf Governorate, Iraq
* Corresponding author: email@example.com
Toxoplasma gondii has a worldwide distribution and it is one of the most prevalent infectious agents in Iraq, as it is found in various mammals, fish, and terrestrial and water birds. Cats are the only definitive host for the parasite that throws the infective phase into the environment. The primary aim of this study was to determine the serum levels of IL-1β, prolactin, Dehydroepiandrosterone (DHEA) in patients and healthy group.The study was conducted on 260 Males suspected of Toxoplasmosis ages ranging from 20-50 years old. All these cases were examined by measuring Toxo IgG serum levels, who attended AL-Hakeem hospital, and (30) healthy males as the control group, collected randomly from AL-Najaf province, these samples were collected from March 2023 to August 2023. Any patient was using the drug or undergoing disease removal from the current study. The current study revealed that the concentration of IL-1β inpatients infected with Toxoplasmosis were significant increase (P<0.05) compared to the control group, but the concentration of (prolactin) in patients infected with toxoplasmosis were significant decrease (P<0.05) is compared to the control group. Also, it revealed that the DHEA levels were elevated but non significantly in samples infected with Toxoplasmosis compared to the control group. The current study has concluded that infection with Toxoplasmosis may be a risk factor. A chronic T. gondii infection is associated with variations in levels of serum prolactin and these variations may influence the immune system by IL-1β increase the susceptibility to Toxoplasmosis infection.
Key words: Najaf / Parasite / T. gondii / IL-1β / DHEA
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.