Milk quality indiators of highly productive cows when using a pharmaceutical composition based on bacteriocin-nizin

FSBSI Ural Federal Agrarian Research Center of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russian Federation

^* Corresponding author: Tmarya105@yandex.ru

Abstract

The article presents data on the effect of a new pharmaceutical composition on milk quality indicators of highly productive cows with a subclinical form of mastitis. The therapeutic efficacy of the new pharmaceutical composition in the treatment regimen of cows with a subclinical form of mastitis was 86.9%. An objective indicator of a healthy udder in cows is the amount of somatic cells contained in milk. After applying the pharmaceutical composition, this indicator decreased by 711.88 thousand/ml. At the end of the experimental period, the average amount of lactoferrin in the milk of cows of the experimental group was 0.35±0.15 mg/ml, which indicates the absence of inflammatory reactions in the mammary gland. It was found that the composition used is effective against such pathogens of mastitis as Staphylococcus aureus, Enterococcus faecium, Streptococcus spp., bacteria of the Escherichia coli group (Escherichia, Enterobacter). Thus, in 60.0% of breast secretion samples from cows of the experimental group, the absence of microflora growth was observed. At the same time, in 40.0% of the samples, the number of colony-forming units of Staphylococcus aureus corresponded to the indicators of normal microflora.