| Issue |
BIO Web Conf.
Volume 111, 2024
2024 6th International Conference on Biotechnology and Biomedicine (ICBB 2024)
|
|
|---|---|---|
| Article Number | 03025 | |
| Number of page(s) | 4 | |
| Section | Medical Testing and Health Technology Integration | |
| DOI | https://doi.org/10.1051/bioconf/202411103025 | |
| Published online | 31 May 2024 | |
CRISPR/Cas System: Mechanisms, Applications, and Limitations
Biochemical engineering, University College London, London WC1E 6BT, UK
* Corresponding author’s e-mail: qytan314@163.com
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated endonuclease 9 (CRISPR/Cas9) gene editing system plays a role in the inhibition of immunity in many bacteria and archaea equips with various advantages such as high efficiency, diversity, and modularity. It is now widely used to improve quality and quantity of crops to satisfy global food demand. Although these prospects are tempting, deeper understanding is still required to improve their efficiency and safety. Therefore, an overview of this special system is important. In this review, the current knowledge of different types of CRISPR/Cas system as well as their mechanisms, applications in crop breeding and limitations is briefly introduced to provide fundamental understanding and guidance for future utilization.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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