| Issue |
BIO Web Conf.
Volume 113, 2024
XVII International Scientific and Practical Conference “State and Development Prospects of Agribusiness” (INTERAGROMASH 2024)
|
|
|---|---|---|
| Article Number | 02020 | |
| Number of page(s) | 9 | |
| Section | Precision Livestock Farming | |
| DOI | https://doi.org/10.1051/bioconf/202411302020 | |
| Published online | 18 June 2024 | |
Effect of growth medium composition on the efficiency of non-ribosomal synthesis in bacteria of the genus Bacillus
1 Southern Federal University, Academy of biology and biotechnology, Stachki Ave., 194/1, Rostov on Don, 344090, Russia
2 Don State Technical University, Gagarin sq. 1, Rostov-on-Don, 344003, Russia
* Corresponding author: vibe@sfedu.ru
Bacteria of the genus Bacillus are known for their ability to suppress a wide range of pathogenic microflora through the production of a variety of secondary metabolites, a significant proportion of which are non-ribosomal peptides. The importance of selecting conditions for the most efficient synthesis of non-ribosomal peptides is related to this. The influence of cultivation conditions can be assessed by analyzing the gene expression of non-ribosomal peptide synthetases of target NRPs and studying the mechanisms of its regulation. The aim of this study is to investigate the influence of growth medium composition on the expression of non-ribosomal peptide synthetase genes in Bacillus bacteria.
Key words: bacillus / NRPS / non-ribosomal synthesis / growth medium / gene regulation
© The Authors, published by EDP Sciences, 2024
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