The effect of a new combined feed on some physiological parameters of laboratory rats

¹ Odesa State Agrarian University, Department of Physiology, Pathophysiology and Biochemistry, 65000, Krasnova st., 3a, Odesa, Ukraine
² Odesa National Medical University, Department of Pharmacology and Pharmacognosy, 65082, Valikhovsky Lane 2, Odesa, Ukraine

^* Corresponding author: yuriyalexb@gmail.com

Abstract

For normal growth, development and vital activity, laboratory animals must receive a complete feed ration. A new feeding ration for rats was proposed, which is based on the use of combined feed PC 120-1. A comparison was made with a standard vivarium ration, which included mostly natural, unprocessed components. To establish the differences between the two rations, changes in the following physiological parameters were studied in experimental animals: body weight, blood composition, blood pressure, and heart rate. It was established that the use of a ration with PC 120-1 combined feed accelerates body weight gain by 5.5%, increases the number of erythrocytes by 23.8%, and hemoglobin by 12.0% compared to animals of the control group. At the same time, under the influence of the applied experimental ration, there was a decrease in blood pressure (by 28%) and heart rate (by 16.6%) in comparison with animals of the control group. Such effects of mixed feed can be explained by a more optimal protein composition and additional addition of a mixture of vitamins and trace elements. Combined fodder is better digested and animals like it better. Recommend further investigation of compound feed PC 120-1 as the main compound feed of vivarium for rats.